Premature ovarian failure (POF), also known as primary ovarian insufficiency, is a condition where the ovaries stop functioning normally before age 40. This results in low estrogen levels and absent or infrequent periods. POF affects approximately 1% of women under the age of 40.
There are several potential causes:
Symptoms include:
Diagnosis involves:
| Diagnostic Method | Description |
|---|---|
| Medical history and physical exam | Reviewing patient's symptoms and medical history |
| Blood tests | Checking FSH and estrogen levels - high FSH and low estrogen point to ovarian failure |
| Imaging tests | Pelvic ultrasound to examine ovarian anatomy |
| Chromosome analysis | Checking for genetic abnormalities |
| Ovarian biopsy | In some cases, to examine ovarian tissue |
As there is no cure, treatment aims to manage symptoms. Options include:
| Treatment Option | Description |
|---|---|
| Hormone replacement therapy (HRT) | Estrogen/progesterone to relieve menopausal symptoms |
| Treatment of underlying autoimmune disorder | If an autoimmune condition is identified |
| Fertility medications or procedures | IVF with donor eggs for pregnancy |
| Counseling and emotional support | To cope with the emotional impact of POF |
The earlier POF is diagnosed, the more treatment options are available. Close monitoring by a gynecologist is recommended. Though the quality of life and outlook for women with POF has improved with advancing treatment options, it remains a challenging diagnosis. At Hormone Health Clinic, we have experience diagnosing and treating ovarian disorders like POF. Our compassionate doctors provide personalized care, hormone replacement therapy, emotional support and a plan for preserving fertility if desired.
In summary, premature ovarian failure is the early loss of normal ovarian function and estrogen production before age 40. It has multiple potential causes, symptoms include irregular periods and menopausal signs, and while there is no cure, symptom management with hormone therapy and emotional support is key. Reach out to fertility and hormone specialists like Hormone Health Clinic for comprehensive POF evaluation and treatment. With proper care and support, women with POF can maintain their health and quality of life.